What changed
Perspective Therapeutics announced a clinical collaboration and supply agreement with Merck to evaluate its targeted alpha-particle therapy [212Pb]PSV359 in combination with Keytruda (pembrolizumab) in FAP-α positive solid tumors. The combination will be tested under an amendment to the ongoing Phase 1/2a study (NCT06710756) in non-small cell lung cancer and colorectal cancer. The study has completed enrollment in the first three monotherapy dose cohorts. Perspective sponsors the study, and Merck provides pembrolizumab at no cost.