SignalFDA/Bio
Telitacicept Demonstrates Durable Preservation of Kidney Function Through Two Years in Phase 3 TELIGAN Trial in IgA Nephropathy
Telitacicept showed two-year kidney function preservation in Phase 3 TELIGAN IgA nephropathy trial.
Context
What happened: Vor Bio reported final two-year results from the Phase 3 TELIGAN trial of telitacicept in adults with IgA nephropathy, conducted in China by collaborator RemeGen.
Why it matters: Vor Bio said the data reinforce the clinical potential of dual BAFF/APRIL inhibition as it advances global Phase 3 programs in myasthenia gravis and Sjögren's disease. Telitacicept received conditional approval in China in June 2026 for proteinuria reduction in primary IgAN.
Market: -6.3% today ($62.65), -14.9% YTD, 0.7x vol — as of 07:45 UTC
What changed
Vor Bio reported final two-year results from the Phase 3 TELIGAN trial of telitacicept in adults with IgA nephropathy, conducted in China by collaborator RemeGen.
Why it matters
Vor Bio said the data reinforce the clinical potential of dual BAFF/APRIL inhibition as it advances global Phase 3 programs in myasthenia gravis and Sjögren's disease. Telitacicept received conditional approval in China in June 2026 for proteinuria reduction in primary IgAN.
Market: -6.3% today ($62.65), -14.9% YTD, 0.7x vol — as of 07:45 UTC