SignalFDA/Bio
Pfizer posts late-stage trial win for multiple myeloma drug Elrexfio in an earlier line setting
Pfizer's late-stage trial win for Elrexfio in earlier multiple myeloma setting signals label expansion.
Context
What happened: Pfizer said its Phase 3 MagnetisMM-32 study of Elrexfio (elranatamab) met its primary endpoint as monotherapy in adults with relapsed or refractory multiple myeloma who received one or more prior lines of therapy.
Key numbers: 523 patients in the international trial. Primary endpoint was progression-free survival.
Why it matters: The result supports Elrexfio in an earlier-line setting, where it is currently approved only after four or more prior therapies. Pfizer will share findings with global health regulators and present detailed results at a future medical event.
Market: -0.8% today ($29.79), +22.3% YTD, 0.7x vol — as of 12:00 UTC
What changed
Pfizer said its Phase 3 MagnetisMM-32 study of Elrexfio (elranatamab) met its primary endpoint as monotherapy in adults with relapsed or refractory multiple myeloma who received one or more prior lines of therapy.
Why it matters
The result supports Elrexfio in an earlier-line setting, where it is currently approved only after four or more prior therapies. Pfizer will share findings with global health regulators and present detailed results at a future medical event.
Market: -0.8% today ($29.79), +22.3% YTD, 0.7x vol — as of 12:00 UTC