SignalFDA/Bio
J&J's oral IL-23 inhibitor ICOTYDE showed sustained skin clearance through Week 112 in Phase 3 plaque psoriasis, including at high-impact sites like scalp, genitals, hands and feet. An oral option com
J&J's oral IL-23 inhibitor ICOTYDE showed sustained skin clearance through Week 112 in Phase 3 plaque psoriasis, including at high-impact sites like scalp, genitals, hands and feet. An oral option com
Context
What happened: Johnson & Johnson reported new Phase 3 results for its oral IL-23 inhibitor ICOTYDE in plaque psoriasis at the 2026 EADV Congress, showing sustained skin clearance and improvement at high-impact sites, including in adolescent patients.
Key numbers: Sustained skin clearance
Why it matters: The content frames an oral option competing with injectable biologics as a pipeline catalyst for $JNJ, with ongoing trials in psoriatic arthritis, ulcerative colitis and Crohn's disease. The stated next test is how the evidence translates into prescribing and reimbursement decisions.
What changed
Johnson & Johnson reported new Phase 3 results for its oral IL-23 inhibitor ICOTYDE in plaque psoriasis at the 2026 EADV Congress, showing sustained skin clearance and improvement at high-impact sites, including in adolescent patients.
Why it matters
The content frames an oral option competing with injectable biologics as a pipeline catalyst for $JNJ, with ongoing trials in psoriatic arthritis, ulcerative colitis and Crohn's disease. The stated next test is how the evidence translates into prescribing and reimbursement decisions.